Purging Unsolicited Comments

Is the absurdity of the spamming situation nowadays apparent to anyone? It's horrible! Not only are email spams the bane of the net, but spammers now target blogs as well. I just finished deleting about 15 spam-comments for what I think might be a German internet "pharmaceutical" company and those damn idiotic penis enlargement pills. Luckily I check the comments regularly and delete nearly all of these rogue annoyances. I'm thinking about looking into blacklisting domains because I don't want to have to enforce some kind of user login for comments. But other than that I'm not really sure what to do. This may require a Google search. But whatever it takes, I'll get these ingrates for profaning by blog with their infernal "mystery" medications and penis enlargement pills!!